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1.
Rev. cuba. farm ; 44(1)ene.-mar. 2010. tab
Article in Spanish | LILACS | ID: lil-576738

ABSTRACT

Como parte de la optimización del proceso tecnológico para obtener citrato de calcio y magnesio a partir de dolomitas, se estudió a escala de banco la etapa de lavado para disminuir el contenido de àcido cítrico libre. Las variantes de lavado estudiadas permitieron disminuir el contenido de àcido cítrico libre por debajo del 3 por ciento, mientras que los valores de calcio y magnesio son similares a los del lote antes de realizar el proceso de lavado. Por otro lado, el estudio toxicológico en ratas, comprobó que los lotes a los cuales se les aplicó las diferentes variantes de lavado no provocaron irritabilidad gástrica a las dosis de 2 000 mg/kg de peso corporal, por lo que se puede afirmar que el proceso de lavado establecido es adecuado para garantizar la calidad de la materia prima.


As part of the technological process optomization to obtain calcium citrate and magnesium from dolomites, we studied at bench scale, the washout stage to decrease the free citric acid content. Washout variants allowed to decrease the free citric acid content under 3 percent, whereas the calcium and magnesium values are similar to those of batch before to carry out the wahout process. On the other hand, toxicity study in rats, proved that the batches where different washout variables were applied not provoke gastric irritability at doses of 2 000 mg/kg of body weight confirming that above mentioned established process is approproate to guarantee the raw material quality.


Subject(s)
Animals , Rats , Citric Acid , Calcium Citrate/isolation & purification , Filtration/methods , Magnesium/isolation & purification
2.
Braz. j. med. biol. res ; 23(12): 1289-302, 1990. ilus, tab
Article in English | LILACS | ID: lil-103658

ABSTRACT

1. We describe a polymeric of magnesium ammonium phosphate associated with linoleic acid and a basic protein produced by Penicillium sp (strain PB-73). 2. Chemical and physical data suggest a structure characterized as an aggregated polymeric form of protein magnesium ammonium phospholinoleate anhydride. 3. The aggregated polymer has an approximate molecular weight of 316 kDa and a phosphate/magnesium ratio of 2.34


Subject(s)
Linoleic Acids/chemistry , Magnesium/isolation & purification , Penicillium/metabolism , Phosphates/isolation & purification , Polymers/isolation & purification , Chromatography, Gel , Fungal Proteins/chemistry , Magnesium/chemistry , Molecular Weight , Penicillium/ultrastructure , Philippines , Phosphates/chemistry
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